Shimadzu NexeraSR ultra-fast liquid chromatography

Nexera SR ultra-fast ultra-fast liquid chromatography liquid chromatography configure new photodiode array detector SPD-M30A of Nexera X2 high-end systems. The new analytical technique with "i-PDeA ※ (patent pending)," provides a new way to not fully resolved peaks or hide peak resolution. With excellent sensitivity and resolution performance, further extends the field UHPLC analysis. Optical system temperature ※ intelligent Peak Deconvolution Analysis Intelligence in UHPLC / HPLC analysis intelligent Peak Deconvolution Analysis (i-PDeA) completely separated unseparated peak Ultimate Sensitivity outstanding high sensitivity Maximized Resolution excellent resolution and a linear spectrum of new design Unrivaled Stability Function TC-Optics achieve stabilization of the baseline intelligent Peak Deconvolution Analysis (i-PDeA, patent pending) completely separated unseparated peak even unseparated peak, if applied i-PDeA feature, you can take advantage of the difference spectra of the extracted single peak, eliminating the trouble unseparated peak waveform processing. Hidden in the destination component peak of the impurity peak in the traditional methods can not detect or can be easily detected, only a few steps to complete testing. Based on i-PDeA waveform processing purposes elution peak tailing on the ... non-destructive quantitative accuracy to the purposes of tailing peaks of the waveform processing i-PdeA outstanding new high-sensitivity photodiode array detector SPD-M30A device uses a high-sensitivity corresponding to low capillary diffusion cell SR-Cell, to achieve superior sensitivity. Reduce the noise level to lead the world's 0.4 × 10 -5 AU less ※, to provide users with an ideal balance between high sensitivity and high separation performance of UHPLC analysis. ※ 2012 in October according to the company's survey uses SR-Cell, both excellent separation performance of high sensitivity and high sensitivity and wide dynamic range, to achieve the main component peak and 0.005% (relative to the main component) minor peak (impurity) The simultaneous quantification of excellent spectral resolution and a linear photodiode array detector SPD-M30A optical system design optimized to provide excellent spectral resolution. With excellent signal processing technology, from low concentrations to high concentrations of a wide spectrum of the region to achieve excellent linearity, it is very suitable for pharmaceutical purity testing and other analyzes requiring wide dynamic range detector. Spectral resolution spectrum index test of benzene. B / A = 2.90 is a leading world class resolution ※. ※: 2012 in November according to the survey, even if the company is different concentration region also received excellent new design of the optical spectra of linear temperature function TC-Optics Department of the baseline stabilized Nexera SR photodiode array detector SPD- M30A is equipped with a newly designed optical system temperature control function (Temperature Controlled Optics, TC-Optics), while using the detection of heat exchange cell inlet portion of the implementation of low diffusion optimized detection cell SR-Cell. For this reason, to achieve a low peak dispersion ultra-fast analysis required, while successfully fast and stable baseline, turn on the power to shorten the analysis after the start of "standby time" to provide a total throughput. Baseline apparatus after start (left)? Measurement conditions (right) is not affected by temperature changes even excellent baseline stability can not be avoided in the air conditioning indoor small temperature variations. TC-Optics equipped with a photodiode array detector SPD-M30A temperature change occurs at baseline remained stable. Changes in room temperature (25 ℃? 30 ℃) and baseline change, and relatively high sensitivity detection cell (optional) other companies PDA device ● Optional additional higher sensitivity detection cell SR-Cell In addition to the standard testing pool, add high sensitivity detection cell. Optical path length of 85 mm, longer than the standard testing pool, fully detect small peaks. Standard flow cell with high sensitivity detection cell of S / N compared alkyl ketones analysis ● pharmaceutical impurity analysis cases high sensitivity detection cell can respond adequately to standard testing pharmaceuticals pool difficult to detect impurities. Use Nexera SR system, were detected in standard cell with high sensitivity detection cell (optional) analyzed Valsartan and its decomposition products. The use of high sensitivity detection cell can detect trace amounts of impurities. Nexera SR system with high sensitivity detection cell combined into a tool for analysis of trace elements. Valsartan impurity analysis of high sensitivity detection sensitivity pool