Supply of imported Du Sheng solid phase peptide synthesis Merrified ion exchange resins

Products for Solid Phase Peptide Synthesis / Combinatorial Chemistry Tulsion? CMB Polymers provide solid phase peptide synthesis and manufacture of special grades biotechnology Temai Shi Du Sheng Biotechnology Polymers for solid phase peptide synthesis steps to use. Thermax make ecial Tulsion? Polymers having applications in the biotechnology area specially for solid phase peptide synthesis. Du Sheng CMB polymer resin having a peptide synthesis can be applied to methyl chloride functional group. In such a resin for peptide synthesis technology is He invented by Merrified in 1963. Peptide bond is a combination of the line into a functional group with an amino acid from the bond of this resin. After removing the protected functional group, a new amino acid molecule is generated to increase its peptide bond. The growth of this peptide bond is a step by step synthetic origin. Filter out the excess reactants in each step. In the final synthesis step is to remove all of the protected functional groups and peptides isolated from this resin. Characteristics of such resins can manufacture according to customer needs, for the application of different synthetic steps. They are manufactured under carefully controlled conditions in accordance with very strict quality standards. Tulsion? CMB polymers have chloromethyl functionality and are used for peptide synthesis.Use of such polymers for peptide synthesis was initiated by Merrifield in 1963. The formation of peptide bond starts with reaction of a protected amino acid molecule with chloromethyl group on the surface of the polystyrene polymer. After removal of the protecting group, a new amino acid molecule is reacted to elongate the peptide chain. The elongation is continued with stepwise addition. Excess reagents and byproducts are removed by filtration at each step. The final step in the synthesis involves freeing up of the protecting group as well as liberating the peptidefrom the polymer Properties of the polymers can be tailor-made to suit individual application needs They are made under very carefully controlled conditions using strictest quality standards Tulsion CB polymers:...? All high base molecule is a synthetic polymer matrix. Tulsion? CB 100/200 is the most common type. The most important consideration for solid phase organic synthesis is the particle size and the expansion factor of the resin. The expansion factor is determined by the characteristics of the resin itself bonded level, hydration and related substances. Tulsion? CB 100/200 itself has very good qualities hydrophobic properties and expands in a non-polar solvent. They used solid phase organic synthesis with DVB cross-bonding and has stable mechanical structure. The foundation of all polymeric synthesis is the polymeric matrix. Tulsion? CB 100/200 is commonly used resin. The most important characteristics considering solid phase organic synthesis are the swelling factor and the bead size of the resin. The swelling characteristics areaffected by the factors such as degree of crosslinking, hydrophobisity of substrate and nature ofthe matrix. Tulsion? CB 100/200 itself is very hydrophobic in nature and swells in a non-polar solvent. It is used in solid phase organic chemistry is crosslinked with DVB to give mechanically stable matrix in presence of swelling solvents. Tulsion? CB 100/200 can be used for various resin synthesis reaction, the reaction as methyl chloride resin or Merrifield resin (Tulsion? CMB), Wang Resins, or for other solid phase peptide synthesis resin. ? Tulsion CB 100/200 resins are used in variety of reactions to give Chloromethyl resins or Merrifield resins (Tulsion CMB?), Wang resins chlorotrytil resins and other resins used in solidphase peptide synthesis technical data Technical Characteristics -.? Tulsion CMB 100 CMB 200 CB 100 CB 200 Structure Matrix Structure Crosslinked Polystyrene crosslinked polystyrene cross-linked polystyrene Crosslinked Polystyrene crosslinked polystyrene Crosslinked Polystyrene Polymer Crosslinked Polystyrene cross-bonded functional groups Functional Group chloromethyl Chloromethyl FB (Free Base). Freedom Plane Polystyrene benzene benzene atmosphere atmosphere Plane Polystyrene particle size Particle Size (ASTM) 100 - 200 200 - 400 100 - 400 200 - 400 Total Chlorine Total Chloride Content (meq / dry gm) 0.8 - 0.4 4 - 0.4 - - Maximum containing water,% Moisture Content Max 1 1 1 1 dissolution rate Solubility insoluble in all solvents Insoluble in all solvent insoluble in all solvents Insoluble in all solvent insoluble in all solvents Insoluble in all solvent insoluble in all solvents Insoluble in all solvent properties Features granular Free flowing spherical beads granular Free flowing spherical beads granular Free flowing spherical beads granular Free flowing spherical beads If you require more detailed information, please contact us