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Clindamycin phosphate Chinese name: Clindamycin phosphate Chinese Synonyms: Clindamycin phosphate; clindamycin phosphate; clindamycin phosphate; clindamycin phosphate; Terri cents; 2- clindamycin phosphate; clindamycin phosphate ester; Clindamycin Phosphate (clindamycin content> 758ΜG / MG, USP32), clindamycin derivatives clindamycin phosphate English name English Name methyl 7- chloro-6,7,8-trideoxy-6- (1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido) -1-thio-l-threo-alpha-d-galacto-octopyranoside 2- (dihydrogen phosphate ); methyl 7-chloro-6,7,8-trideoxy-6 - [(1-methyl-4-propylprolyl) amino] -2-O-phosphono-1-thiooctopyranoside; methyl 7-chloro-6,7,8 -trideoxy-6 - {[(4R) -1-methyl-4-propyl-L-prolyl] amino} -2-O-phosphono-1-thiooctopyranoside; methyl 7-chloro-6,7,8-trideoxy-6 - {[(4R) -1-methyl-4-propyl-L-prolyl] amino} -2-O-phosphono-1-thio-L-threo-alpha-D-galacto-octopyranoside; [(2R, 3R, 4S, 5R, 6R) -6- [2-chloro-1 - [[(2S, 4R) -1-methyl-4-propyl-pyrrolidine-2-carbonyl] amino] propyl] -4,5-dihydroxy-2 -methylsulfanyl-tetrahydropyran-3-yl] dihydrogen phosphate Related Categories: Antibiotics for Research and Experimental Use; Biochemistry; Others (Antibiotics for Research and Experimental Use); Pharmaceuticals; API; API's; Intermediates & Fine Chemicals; Pharmaceuticals; microbial metabolites; lincosamides drug; antibiotic EINECS: 246-433-0 Molecular formula: C18H34CLN2O8PS Molecular Weight: 504.96 CAS NO: .24729-96-2 Appearance: white or almost white crystalline powder Content: 98% Melting Point: 114 ° C refractive index: 122 ° (C = 1, H2O) storage conditions: 2-8 ° C Merck: 2356 Mol File: 24729-96-2.mol and Synthesis: Brooklyn derivative clindamycin antibiotic medicines ADM phosphate chemical semi-synthetic derivative clindamycin, at room temperature, white or almost white crystalline powder, odorless, bitter, wet primer. No antibacterial activity in vitro, into the body rapidly hydrolyzed to clindamycin can play a pharmacological effect. Its mechanism of action, antimicrobial spectrum, indications, treatment with clindamycin same, but its fat-soluble and permeable Bike Lin adriamycin, and can also be oral and intravenous intramuscular administration, mainly in the liver metabolism, bile and fecal excretion, partially excreted in the urine. Compared with lincomycin, clindamycin phosphate strong antibacterial activity of 4 to 8 times, absorption, high bone tissue concentrations of Gram-positive cocci, and anaerobic bacteria have strong antibacterial activity. Its antibacterial spectrum is: Gram-positive cocci including penicillin G-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (Streptococcus except phosphorus), Streptococcus pneumoniae, Micrococcus and the like; Gram-positive bacilli including Clostridium bacillus, diphtheria bacillus; anaerobes including Clostridium, Bacteroides, Clostridium, Propionibacterium acnes are really bacteria, anaerobic bacteria and the like. The clindamycin phosphate mainly used for clinical treatment of tonsillitis, otitis media, sinusitis, acute bronchitis, acute exacerbation of chronic bronchitis, pneumonia, lung abscess, bronchiectasis with infection and skin and soft tissue infections, such as boils, carbuncles , abscesses, cellulitis, wound infections, infected burns, post-operative infections, urinary tract and acute urethritis, acute pyelonephritis, prostatitis, etc., but also for osteomyelitis, sepsis, peritonitis, oral infections.